Article
Maternal Continuous Oral Oxycodone Self-Administration Alters Pup Affective/Social Communication but not Spatial Learning or Sensory-Motor Function
2020-04-05
Abstract excerpt
The broad use and misuse of prescription opioids during pregnancy has resulted in a surge of infants diagnosed with Neonatal Opioid Withdrawal Syndrome (NOWS). Short-term irritability and neurological complications are hallmarks of NOWS, but the long-term consequences are unknown. Our newly-developed preclinical model of oxycodone self-administration enables adult female rats to readily drink oxycodone (0.06-0.12...
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Identifiers and source
- Literature Corpus work
- b72872e2-7687-5a9a-b8f2-0ef84d0ff4eb
- DOI
- 10.1101/2020.04.04.022533
