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Structure, function and variants analysis of the androgen-regulated <i>TMPRSS2</i> , a drug target candidate for COVID-19 infection

2020-05-26

Abstract excerpt

SARS-CoV-2 is a novel virus causing mainly respiratory, but also gastrointestinal symptoms. Elucidating the molecular processes underlying SARS-CoV-2 infection, and how the genetic background of an individual is responsible for the variability in clinical presentation and severity of COVID-19 is essential in understanding this disease. Cell infection by the SARS-CoV-2 virus requires binding of its Spike (S) protei...

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Literature Corpus work
d18335cb-6102-5a31-95e0-10c503fa25c3
DOI
10.1101/2020.05.26.116608
Open publication

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Structure, function and variants analysis of the androgen-regulated <i>TMPRSS2</i> , a drug target candidate for COVID-19 infectionDOI 10.1101/2020.05.26.116608
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