Article
COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells.
Genes - 27 Aug 2020
Latini Andrea, Agolini Emanuele, Novelli Antonio, Borgiani Paola, Giannini Rosalinda, Gravina Paolo, Smarrazzo Andrea, Dauri Mario, Andreoni Massimo, Rogliani Paola, Bernardini Sergio, Helmer-Citterich Manuela, Biancolella Michela, Novelli Giuseppe
Abstract excerpt
The recent global COVID-19 public health emergency is caused by SARS-CoV-2 infections and can manifest extremely variable clinical symptoms. Host human genetic variability could influence susceptibility and response to infection. It is known that ACE2 acts as a receptor for this pathogen, but the viral entry into the target cell also depends on other proteins. The aim of this study was to investigate the...
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