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Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice

2022-01-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> There is mounting evidence that microbes resident in the human intestine contribute to diverse alcohol-associated liver diseases (ALD) including the most deadly form known as alcohol-associated hepatitis (AH). However, mechanisms by which gut microbes synergize with excessive alcohol intake to promote liver injury are poorly understood. Furthermore, whether drugs that select...

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Literature Corpus work
d17b6482-56b1-5530-8304-05fca3bfa541
DOI
10.1101/2021.12.31.474633
Open publication

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Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in MiceDOI 10.1101/2021.12.31.474633
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