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Host-Microbiome Interactions in Alcoholic Liver Disease

15 May 2014

Abstract excerpt

Alcoholic liver disease is a leading cause of morbidity and liver-related death worldwide. Intestinal bacterial overgrowth and dysbiosis induced by ethanol ingestion play an important role in the pathogenesis of alcoholic liver disease. After exposure to alcohol in the lumen, enteric bacteria alter their metabolism and thereby disturb intestinal homeostasis. Disruption of the mucosal barrier results in the...

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PMID: 24827618
DOI: 10.5009/gnl.2014.8.3.237

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