Article

Meiotic crossover patterning in the absence of ATR: Loss of interference and assurance but not the centromere effect

2017-05-29

Abstract excerpt

<h4>ABSTRACT</h4> Meiotic crossovers must be properly patterned to ensure accurate disjunction of homologous chromosomes during meiosis I. Disruption of the spatial distribution of crossovers can lead to nondisjunction, aneuploidy, gamete dysfunction, miscarriage, or birth defects. One of the earliest identified genes in involved proper crossover patterning is textitDrosophila mei-41, which encodes the ortholog o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d13fe716-e48f-5c42-a658-6c2e22e9815a
DOI: 10.1101/143651

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Meiotic crossover patterning in the absence of ATR: Loss of interference and assurance but not the centromere effectDOI 10.1101/143651Read

Loss of Drosophila Mei-41/ATR Alters Meiotic Crossover Patterning.Semantic proximity Read

Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutants.Semantic proximity Read

Identification of novel Drosophila meiotic genes recovered in a P-element screen.Semantic proximity Read

Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation.Semantic proximity Read

Studies on crossover-specific mutants and the distribution of crossing over in Drosophila females.Semantic proximity Read

Genetic control of mitotic-to-meiotic transition regulates germline cell survivalSemantic proximity Read

Crossover patterns under meiotic chromosome programSemantic proximity Read

Two genes required for meiotic recombination in Drosophila are expressed from a dicistronic message.Semantic proximity Read

Variation in crossover frequencies perturb crossover assurance without affecting meiotic chromosome segregation in Saccharomyces cerevisiae.Semantic proximity Read

A genome-wide atlas of meiotic recombination intermediates reveals distinct modes of DNA repair that direct crossovers away from transcriptionally marked genesSemantic proximity Read

Topoisomerase II mediates meiotic crossover interference.Semantic proximity Read

<i>mlh3</i> separation of function and endonuclease defective mutants display an unexpected effect on meiotic recombination outcomesSemantic proximity Read