Article

Distribution of Huntington’s disease Haplogroups in Indian population

2021-01-03

Abstract excerpt

Huntington’s disease (HD), a rare neurodegenerative disorder, is inherited in an autosomal dominant manner, and caused by a pathological trinucleotide expansion at exon1 of the HTT locus. Previous studies have described the haplogroups at the HTT locus that can explain the differences in prevalence of HD. We have selected three informative SNPs (rs762855, rs3856973 and rs4690073) to study these haplogroups in an...

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Literature Corpus work: d1329aa5-79da-5466-aa87-cead8c92a721
DOI: 10.1101/2020.12.31.424975

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