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Exosomal ANGPTL1 Attenuates Colorectal Cancer Liver Metastasis by Regulating Kupffer Cell Secretion Pattern and Impeding MMP9 Induced Vascular Leakiness

2020-12-08

Abstract excerpt

<h4>Background: </h4> Angiopoietin-like protein 1 (ANGPTL1) has been proved to suppress tumor metastasis in several cancers. However, its extracellular effects on the pre-metastatic niches (PMNs) are still unclear. ANGPTL1 has been identified in exosomes, while its function remains unknown. This study was designed to explore the role of exosomal ANGPTL1 on liver metastasis in colorectal cancer (CRC). <h4>Methods:...

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Literature Corpus work
d1224620-deb7-5db4-a29a-122ff30bf6cd
DOI
10.21203/rs.3.rs-66235/v2
Open publication

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Exosomal ANGPTL1 Attenuates Colorectal Cancer Liver Metastasis by Regulating Kupffer Cell Secretion Pattern and Impeding MMP9 Induced Vascular LeakinessDOI 10.21203/rs.3.rs-66235/v2
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