Article
Liver prometastatic reaction: Stimulating factors and responsive cancer phenotypes.
Seminars in cancer biology - 1 Jun 2021
Vidal-Vanaclocha Fernando, Crende Olatz, García de Durango Cira, Herreros-Pomares Alejandro, López-Doménech Sandra, González Álvaro, Ruiz-Casares Eva, Vilboux Thierry, Caruso Riccardo, Durán Hipólito, Gil Antonio, Ielpo Benedetto, Lapuente Fernando, Quijano Yolanda, Vicente Emilio, Vidal-Lartitegui Leticia, Sotomayor Eduardo M
Abstract excerpt
Cancer is first a localized tissue disorder, whose soluble and exosomal molecules and invasive cells induce a host response providing the stromal components of the primary tumor microenvironment (TME). Once the TME is developed, cancer-derived molecules and cells can more efficiently spread out and a whole-body response takes place, whose pathophysiological changes may result in a paraneoplastic syndrome. Remote...
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