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Age and sex effects on blood retrotransposable element expression levels: Findings from the population-based Rhineland Study

2024-12-17

Abstract excerpt

Retrotransposable elements (RTEs) have been implicated in the pathogenesis of several age-associated diseases. Although model systems indicate that age- and sex-dependent loss of heterochromatin increases RTE expression, data from large human studies are lacking. Here we assessed the expression levels of 795 blood RTE subfamilies in 2467 participants of the population-based Rhineland Study. We found that the expre...

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Literature Corpus work
d10b52dc-6bf8-5954-b89a-1cad61033430
DOI
10.1101/2024.12.17.24319143
Open publication

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Age and sex effects on blood retrotransposable element expression levels: Findings from the population-based Rhineland StudyDOI 10.1101/2024.12.17.24319143
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