Article

5’ Untranslated mRNA Regions Allow Bypass of Host Cell Translation Inhibition by <i>Legionella pneumophila</i>

2022-04-30

Abstract excerpt

Legionella pneumophila grows within membrane-bound vacuoles in alveolar macrophages during human disease. Pathogen manipulation of the host cell is driven by bacterial proteins translocated through a type IV secretion system (T4SS). Although host protein synthesis during infection is arrested by the action of several of these translocated effectors, translation of a subset of host proteins predicted to restrict th...

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Literature Corpus work: d0d575ae-5385-5a1c-b21f-0b03e7f7b985
DOI: 10.1101/2022.04.29.490120

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