Article
Global translation variations in host cells upon attack of lytic and sublytic Staphylococcus aureus α-haemolysin.
The Biochemical journal - 15 Nov 2015
Clamer Massimiliano, Tebaldi Toma, Marchioretto Marta, Bernabò Paola, Bertini Efrem, Guella Graziano, Dalla Serra Mauro, Quattrone Alessandro, Viero Gabriella
Abstract excerpt
Genome-wide analyses of translation can provide major contributions in our understanding of the complex interplay between virulent factors and host cells. So far, the activation of host translational control mechanisms by bacterial toxins, owing to specific recruitment of mRNAs, RNA-binding proteins (RBPs) and ncRNAs (non-coding RNAs), are far from being understood. In the present study, we characterize for the...
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