Article

Hypoxia Promotes Osteoclast Differentiation through Weakening the USP18-Mediated Suppression on NF-κB Signaling Pathway

2024-10-18

Abstract excerpt

<h4>Background: </h4> Osteoporosis, a prevalent metabolic bone disorder, is characterized by reduced bone density and increased fracture risk. The pathogenesis of osteoporosis is closely associated with an imbalance in bone remodeling, where the resorption function of osteoclasts exceeds the formation function of osteoblasts. Hypoxia has been implicated in the promotion of osteoclast differentiation and the subseq...

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Literature Corpus work: d0d2b2e3-3edd-5f35-a3d2-25528fe0dbe2
DOI: 10.20944/preprints202410.1450.v1

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