Article

PSMB9 Exacerbates Chondrocyte Injury in Osteoarthritis via Activation of the NF-κB Pathway

2025-12-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation and synovial inflammation, with its pathogenesis being incompletely understood. This study aimed to investigate the role and mechanism of PSMB9 in interleukin-1β (IL-1β)-induced chondrocyte injury. <bold>Methods:</bold> We identified OA-associated proteasome members b...

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Literature Corpus work: 79d0b2f2-9a5d-52db-98ce-0cffacfb3205
DOI: 10.21203/rs.3.rs-8216872/v1

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