Article

The Human Milk Oligosaccharide 3’Sialyllactose Promotes Inflammation Resolution and Reduces Atherosclerosis Development in Mice

2021-03-20

Abstract excerpt

<h4>SUMMARY</h4> Macrophages contribute to the induction and resolution of inflammation and play a central role in the chronic low-grade inflammation in cardiovascular diseases caused by atherosclerosis. Human milk oligosaccharides (HMOs) are complex unconjugated glycans unique to human milk that benefit infant health and act as innate immune modulators. Here, we identify the HMO 3’sialyllactose (3’SL) as a natur...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d0cdbe6d-5458-5485-b6dd-3a9cff4f9e91
DOI: 10.1101/2021.03.19.433472

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Human Milk Oligosaccharide 3’Sialyllactose Promotes Inflammation Resolution and Reduces Atherosclerosis Development in MiceDOI 10.1101/2021.03.19.433472Read

Human milk oligosaccharides: The role in the fine-tuning of innate immune responsesSemantic proximity Read

Human milk oligosaccharides regulate human macrophage polarization and activation in response to Staphylococcus aureusSemantic proximity Read

Human milk oligosaccharides are associated with maternal genetics and respiratory health of human milk-fed children.Semantic proximity Read

Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multiomics integrationSemantic proximity Read

Fucosylated Human Milk Oligosaccharides and N-Glycans in the Milk of Chinese Mothers Regulate the Gut Microbiome of Their Breast-Fed Infants during Different Lactation StagesSemantic proximity Read

Bacterial clearance enhanced by α2, 3- and α2, 6-sialyllactose via receptor-mediated endocytosis and phagocytosisSemantic proximity Read

Systematic Characterization and Longitudinal Study Reveal Distinguishing Features of Human Milk Oligosaccharides in ChinaSemantic proximity Read

Integrated ‘omics analysis reveals human milk oligosaccharide biosynthesis programs in human lactocytesSemantic proximity Read

In silico analysis of the human milk oligosaccharide glycome reveals key enzymes of their biosynthesisSemantic proximity Read

New Insights into Human Milk Oligosaccharide Profiles in China: Findings from a Large-Scale Analysis of Human Milk.Semantic proximity Read

Comprehensive profiles of human milk oligosaccharides yield highly sensitive and specific markers for determining secretor status in lactating mothers.Semantic proximity Read

Decidual glycodelin-A polarizes human monocytes into a decidual macrophage-like phenotype through Siglec-7.Semantic proximity Read