Article

Integrated ‘omics analysis reveals human milk oligosaccharide biosynthesis programs in human lactocytes

2025-03-18

Abstract excerpt

Human milk oligosaccharides (HMOs) are integral to infant health. Yet, their complex biosynthesis pathways in the mammary gland during lactation remain under characterized. To address this knowledge gap, we performed integrated analyses of single-cell RNA-sequencing (scRNA-seq) datasets combined with select HMO concentration measures. We identify differential expression patterns of known HMO synthesis genes in epi...

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Literature Corpus work: 4dfea236-dd7d-542c-b68d-1254321884ae
DOI: 10.1101/2025.03.17.643803

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