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Article

Comprehensive profiles of human milk oligosaccharides yield highly sensitive and specific markers for determining secretor status in lactating mothers.

Journal of proteome research - 7 Dec 2012

Totten Sarah M, Zivkovic Angela M, Wu Shuai, Ngyuen UyenThao, Freeman Samara L, Ruhaak L Renee, Darboe Momodou K, German J Bruce, Prentice Andrew M, Lebrilla Carlito B

Abstract excerpt

Human milk oligosaccharides (HMOs), as an abundant and bioactive component of breast milk, work in many ways to promote the health of breast fed infants. The expression of HMOs has been shown to vary in accordance with Lewis blood type and secretor status, as women of different blood types differ in the expression of α1,2 fucosyltransferase (FUT2) and α1,3/4 fucosyltransferase (FUT3). In this study, HMOs were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23140396
DOI: 10.1021/pr300769g

Genes

FUT2
FUT3

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