Human milk oligosaccharides regulate human macrophage polarization and activation in response to Staphylococcus aureus

Abstract excerpt

Human milk oligosaccharides (HMOs) are present in high numbers in milk of lactating women. They are beneficial to gut health and the habitant microbiota, but less is known about their effect on cells from the immune system. In this study, we investigated the direct effect of three structurally different HMOs on human derived macrophages before challenge with Staphylococcus aureus ( S. aureus ). The study...

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