Article

Complex Indel Detection: A Simulation-Based Framework and Parsing with FreeBayes

2026-05-29

Abstract excerpt

<h4>ABSTRACT</h4> In contrast to simple deletions and simple insertions, most complex indels involve both deletions and insertions, often with base changes within a few nucleotides of the indel’s left and right boundaries. These complex indels often arise from double-strand breaks (DSB), which in normal somatic cells are predominantly repaired by nonhomologous DNA end joining (NHEJ). Such complex indels pose a di...

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Literature Corpus work: d0c6d028-3ea8-5d3c-915e-546acadef38f
DOI: 10.64898/2026.05.26.727999

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