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PDE6G inhibits the expression of CD71 in erythroid progenitor cells through the PDE6G/BHLHE40/miR144-3p/CD71 pathway, leading to red cell production obstacles and ultimately causing anemia in myelofibrosis

2024-05-28

Abstract excerpt

<title>Abstract</title> <p>Myelofibrosis(MF) is a haematological malignancy. Most patients with MF will develop mild to moderate anemia. The MF-related anemia results from multifactorial factors. At present, the molecular mechanisms leading to MF-related anemia are still not fully understood. This study aimed to explore the role of PDE6G in MF-related anemia, verify its effect on the differentiation of erythroid...

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Literature Corpus work: d0bf82f5-be65-53ed-b2d6-81e0e970cd7c
DOI: 10.21203/rs.3.rs-4313987/v1

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PDE6G inhibits the expression of CD71 in erythroid progenitor cells through the PDE6G/BHLHE40/miR144-3p/CD71 pathway, leading to red cell production obstacles and ultimately causing anemia in myelofibrosisDOI 10.21203/rs.3.rs-4313987/v1Read

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