Article

Patient-Derived Three-Dimensional Cortical Neurospheres to Model Parkinson’s Disease

2021-08-23

Abstract excerpt

There are currently no preventive or disease-modifying therapies for Parkinson’s Disease (PD). Failures in clinical trials necessitate a re-evaluation of existing pre-clinical models in order to adopt systems that better recapitulate underlying disease mechanisms and better predict clinical outcomes. In recent years, models utilizing patient-derived induced pluripotent stem cells (iPSCs) have emerged as attractive...

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Literature Corpus work: d08b0157-4b5b-539b-a0e8-22cb9a771ed7
DOI: 10.1101/2021.08.21.457201

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