Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organoid and pluripotent stem cells in Parkinson’s disease modeling: an expert view on their value to drug discovery

3 Jan 2020

Abstract excerpt

Introduction: Parkinson’s disease is a devastating neurodegenerative disorder preferentially involving loss of dopaminergic neurons in the substantia nigra, leading to typical motor symptoms. While there are still no therapeutics to modify disease course, recent work using induced pluripotent stem cell (iPSC) and 3D brain organoid models have provided further insight into Parkinson’s disease pathogenesis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurological disorders and treatments
Share to Nuclear Receptors and Signaling
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31899983
DOI: 10.1080/17460441.2020.1703671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Organoid and pluripotent stem cells in Parkinson’s disease modeling: an expert view on their value to drug discoveryPMID 31899983Read ↗

Modeling Parkinson’s Disease Using Patient-specific Induced Pluripotent Stem CellsSemantic proximity Read ↗

Modeling Cell-Cell Interactions in Parkinson’s Disease Using Human Stem Cell-Based ModelsSemantic proximity Read ↗

Brain Organoids in Parkinson’s Disease Drug Development: Human-Specific Models for Translational DiscoverySemantic proximity Read ↗

Induced Pluripotent Stem Cells in Drug Discovery and Neurodegenerative Disease ModelingSemantic proximity Read ↗

Induced pluripotent stem cells and Parkinson's disease: modelling and treatmentSemantic proximity Read ↗

Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challengesSemantic proximity Read ↗

Stem cell therapy for Parkinson’s disease: safety and modelingSemantic proximity Read ↗

Using induced pluripotent stem cells for modeling Parkinson’s diseaseSemantic proximity Read ↗

Modeling Parkinson’s Disease Using Induced Pluripotent Stem CellsSemantic proximity Read ↗

Human Induced Pluripotent Stem Cell Phenotyping and Preclinical Modeling of Familial Parkinson’s DiseaseSemantic proximity Read ↗

Parkinson's disease in a dish - Using stem cells as a molecular tool.Semantic proximity Read ↗

Mosaic midbrain organoids: a new tool to study Progressive Supranuclear Palsy and advancing clinical neurology researchSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.