Article

Acute IFN-γ responses drive sensory neuron injury and chronic pain after chikungunya virus infection

2026-02-03

Abstract excerpt

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes acute and chronic musculoskeletal disease characterized by often debilitating pain; however, the mechanisms associated with the pain remain understudied. Here, we used an experimental mouse model and patients to investigate the role of interferon-γ (IFN-γ) in the pain during chronic inflammation after CHIKV infection. Our data show that CHIKV ind...

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Literature Corpus work: d01dce4b-3b68-5623-8df2-49397647b9b1
DOI: 10.64898/2026.02.02.702518

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