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Article

Novel Lesions of Bones and Joints Associated with Chikungunya Virus Infection in Two Mouse Models of Disease: New Insights into Disease Pathogenesis.

PloS one - 1 Jan 2016

Goupil Brad A, McNulty Margaret A, Martin Matthew J, McCracken Michael K, Christofferson Rebecca C, Mores Christopher N

Abstract excerpt

Chikungunya virus is an arbovirus spread predominantly by Aedes aegypti and Ae. albopictus mosquitoes, and causes debilitating arthralgia and arthritis. While these are common manifestations during acute infection and it has been suggested they can recur in patients chronically, gaps in knowledge regarding the pathogenesis still exist. Two established mouse models were utilized (adult IRF 3/7 -/- -/- and...

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Identifiers

PMID: 27182740
DOI: 10.1371/journal.pone.0155243
PMCID: PMC4868286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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