Article

Immune Deficiency and Immune Dysregulation in Single-Ventricle Congenital Heart Disease: A Forgotten Multidimensional Problem

2026-05-25

Abstract excerpt

Children with single-ventricle congenital heart disease represent a uniquely vulnerable population in whom immune dysfunction remains underrecognized despite increasing evidence of clinically significant abnormalities affecting both innate and adaptive immunity. Emerging data suggest that immune injury in these patients is multifactorial and cumulative. Early thymectomy during congenital cardiac surgery may impair...

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Literature Corpus work: cffb5503-a66e-578f-bf72-f8b1105ea06e
DOI: 10.20944/preprints202605.1643.v1

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