Article

Characterization of Natural Killer Cell Subpopulations in the Blood of Single Ventricle/Hypoplastic Left Heart Syndrome Patients Using Single-Cell RNA Sequencing

2024-08-19

Abstract excerpt

We utilized single-cell RNA sequencing (scRNA-seq) to examine peripheral blood mononuclear cells (PBMCs) from patients with Single Ventricle/Hypoplastic Left Heart Syndrome (SV/HLHS), and demonstrated a more pronounced correlation between gene expression in Natural Killer (NK) cells and SV/HLHS compared to other PBMC cell types. Our scRNA-seq analysis of NK cells in this study identified two distinct clusters with...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: baea9010-4a09-5b7d-95de-e78be533e0d6
DOI: 10.1101/2024.08.18.24312189

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterization of Natural Killer Cell Subpopulations in the Blood of Single Ventricle/Hypoplastic Left Heart Syndrome Patients Using Single-Cell RNA SequencingDOI 10.1101/2024.08.18.24312189Read

Single-cell RNA Sequencing of Peripheral Blood Mononuclear Cells in Patients with Single Ventricle/Hypoplastic Left Heart SyndromeSemantic proximity Read

High-Dimensional Single-Cell Analysis of Natural Killer Cell Heterogeneity in Human BloodSemantic proximity Read

Single-Cell RNA-Seq Analysis Uncovers Distinct Functional Human NKT Cell Sub-Populations in Peripheral BloodSemantic proximity Read

Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patientsSemantic proximity Read

Utilizing single-cell RNA sequencing for analyzing the characteristics of PBMC in patients with Kawasaki diseaseSemantic proximity Read

Single‐cell RNA sequencing reveals the altered innate immunity in immune checkpoint inhibitor‐related myocarditisSemantic proximity Read

Aberrant peripheral immune responses in acute Kawasaki disease with single-cell sequencingSemantic proximity Read

Utilizing Single-cell RNA Sequencing for Analyzing the Characteristics of PBMC in Patients with Kawasaki DiseaseSemantic proximity Read

Single-Cell RNA Sequencing Reveals the Altered Landscape of Immune Cells in Immune Checkpoint Inhibitor Related MyocarditisSemantic proximity Read

Methods for Isolating and Defining Single-Cell Transcriptomes of Tissue-Resident Human NK Cells.Semantic proximity Read

Single-cell RNA-seq reveals altered plasma cell subsets and decreased cytotoxicity of NK cells in patients with Kawasaki diseaseSemantic proximity Read