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Article

Early Thymectomy Is Associated With Long-Term Impairment of the Immune System: A Systematic Review.

Frontiers in immunology - 1 Jan 2021

Cavalcanti Nara Vasconcelos, Palmeira Patrícia, Jatene Marcelo Biscegli, de Barros Dorna Mayra, Carneiro-Sampaio Magda

Abstract excerpt

Background and Aims: Congenital heart diseases (CHDs) are diagnosed in approximately 9 in 1,000 newborns, and early cardiac corrective surgery often requires partial or complete thymectomy. As the long-term effect of early thymectomy on the subsequent development of the immune system in humans has not been completely elucidated, the present study aimed to evaluate the effects of thymus removal on the functional...

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Identifiers

PMID: 34899730
DOI: 10.3389/fimmu.2021.774780
PMCID: PMC8656688

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