Article
Lymphocyte Immune Response and T Cell Differentiation in Fontan Patients with protein-losing enteropathy.
The Thoracic and cardiovascular surgeon - 1 Dec 2021
Moosmann Julia, Toka Okan, Lukassen Sören, Ekici Arif B, Mackensen Andreas, Völkl Simon, Dittrich Sven
Abstract excerpt
BACKGROUND: Protein-losing enteropathy (PLE) is a severe complication of the Fontan circulation. There is increasing discussion about whether lymphatic dysregulation is involved as pathomechanism of PLE. This investigation focuses on the interplay between alteration of lymphatic cells and immunologic pathway alterations. METHODS: Micro-ribonucleic acid (miRNA) expression profiling was performed in 49 patients...
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