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Porcine reproductive and respiratory syndrome virus nonstructural protein 2 contributes to NF-κB activation

30 Apr 2012

Abstract excerpt

BACKGROUND: Nuclear factor-kappaB (NF-κB) is an inducible transcription factor that plays a key role in inflammation and immune responses, as well as in the regulation of cell proliferation and survival. Previous studies by our group and others have demonstrated that porcine reproductive and respiratory syndrome virus (PRRSV) infection could activate NF-κB in MARC-145 cells and alveolar macrophages. The...

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PMID: 22546080
DOI: 10.1186/1743-422x-9-83

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