Article

An Insectified Caco-2 Cell-Based assay to monitor pesticide Transport Processes and Pharmacokinetics

2026-07-24

Abstract excerpt

Intestinal insect cells are integral to pharmacokinetic research, unfortunately they do not serve as cell models for more advanced studies comparable to transport studies typically conducted in mammalian models. To overcome this limitation, in this study, we developed a Caco-2 cell line that has been genetically modified to mimic insect-like characteristics, providing a robust ‘insectified’ screening platform to m...

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Literature Corpus work: cfb84d86-132e-5c32-a6ff-7e04319a0dbe
DOI: 10.64898/2026.07.21.739763

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