Article

Validation of an MPS based intestinal cell culture model for the evaluation of drug-induced toxicity

2024-07-22

Abstract excerpt

The potential for drug-induced gastrointestinal (GI) toxicity is significant, since the GI tract is one of the first barriers which come in to contact with oral drugs. In pharmaceutical research, the complex behavior of human intestinal cells is traditionally investigated using 2D cultures, in which one cell type grows under static conditions. With the development of advanced microphysiological systems (MPS) more...

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Literature Corpus work: 0529a8b3-3c6d-5518-bdad-741b0f1a0fdb
DOI: 10.1101/2024.07.18.604106

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