Article

Differences in innate Intracellular viral suppression competencies may explain variations in morbidity and mortality from SARS-CoV-2 infection

2020-09-14

Abstract excerpt

SARS-CoV-2 infection and COVID-19 ravage the world with wide variations in morbidity and mortality that have remained largely unexplained, even by mutations in protein coding regions. In this study, we analyzed available complete SARS-CoV-2 sequences using the CpG index as a signature of Zinc finger antiviral protein (ZAP) activity to examine population variations in innate intracellular antiviral competencies. Th...

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Literature Corpus work: cfa506a0-f635-5fe7-9bed-087c52906bb4
DOI: 10.1101/2020.09.13.20193524

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