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Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons

8 Nov 2021

Abstract excerpt

Somatosensory neurons with cell bodies in the dorsal root ganglia (DRG) project to the skin, muscles, bones, and viscera to detect touch and temperature as well as to mediate proprioception and many types of interoception. In addition, the somatosensory system conveys the clinically relevant noxious sensations of pain and itch. Here, we used single nuclear transcriptomics to characterize transcriptomic classes of...

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PMID: 34825887
DOI: 10.7554/elife.71752

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