Article

Calcium and Bicarbonate Signaling Pathways have Pivotal, Resonating Roles in Matching ATP Production to Demand

2022-11-01

Abstract excerpt

Mitochondrial ATP production in cardiac ventricular myocytes must be continually adjusted to rapidly replenish the ATP consumed by the working heart. Two systems are known to be critical in this regulation: mitochondrial matrix Ca 2+ ([Ca 2+ ] m ) and blood flow that is tuned by local ventricular myocyte metabolic signaling. However, these two regulatory systems do not account for the large physiological range...

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Literature Corpus work: cf33f6b2-ad17-5700-bdef-8e99bb4efba5
DOI: 10.1101/2022.10.31.514581

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