Article

Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities

2023-01-20

Abstract excerpt

Models to study metastatic disease in rare cancers are needed to advance preclinical therapeutics and to gain insight into disease biology, especially for highly aggressive cancers with a propensity for metastatic spread. Osteosarcoma is a rare cancer with a complex genomic landscape in which outcomes for patients with metastatic disease are poor. As osteosarcoma genomes are highly heterogeneous, a large panel of...

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Literature Corpus work: 13e656ea-55ea-5ca1-bc86-36f6f42d6852
DOI: 10.1101/2023.01.19.524562

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