Article

Characterization and clustering of kinase isoform expression in metastatic melanoma

2021-08-06

Abstract excerpt

Mutations to the human kinome are known to play causal roles in cancer. The kinome regulates numerous cell processes including growth, proliferation, differentiation, and apoptosis. In addition to aberrant expression, aberrant alternative splicing of cancer-driver genes is receiving increased attention as it could create loss or gain of functional domains, altering a kinase’s downstream effects. The present study...

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Literature Corpus work: ceb6c739-ad59-59db-9c09-b4407b6c144f
DOI: 10.1101/2021.08.05.455315

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