Article
A Transcriptome-Wide Isoform Landscape of Melanocytic Nevi and Primary Melanomas Identifies Gene Isoforms Associated with Malignancy.
International journal of molecular sciences - 2 Jul 2021
Hakobyan Siras, Loeffler-Wirth Henry, Arakelyan Arsen, Binder Hans, Kunz Manfred
Abstract excerpt
Genetic splice variants have become of central interest in recent years, as they play an important role in different cancers. Little is known about splice variants in melanoma. Here, we analyzed a genome-wide transcriptomic dataset of benign melanocytic nevi and primary melanomas (n = 80) for the expression of specific splice variants. Using kallisto, a map for differentially expressed splice variants in melanoma...
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