Article

Learning Genetic Perturbation Effects with Variational Causal Inference

2025-06-05

Abstract excerpt

Advances in sequencing technologies have enhanced the understanding of gene regulation in cells. In particular, Perturb-seq has enabled high-resolution profiling of the transcriptomic response to genetic perturbations at the single-cell level. This understanding has implications in functional genomics and potentially for identifying therapeutic targets. Various computational models have been developed to predict p...

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Literature Corpus work: 2b527efe-d43f-51a3-b2ca-5ca937595196
DOI: 10.1101/2025.06.05.657988

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