Article
Cardiovascular disease causes proinflammatory microvascular changes in the human right atrium
2021-06-24
Abstract excerpt
Ischemic heart disease is globally the leading cause of death. It plays a central role in the electrical and structural remodeling of the right atrium, predisposing to arrhythmias, heart failure, and sudden death. Here, we provide the first dissection of the gene expression changes in the live right atrial tissue, using single-nuclei RNA-seq and spatial transcriptomics. We investigate matched samples of the tissue...
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Identifiers and source
- Literature Corpus work
- 43cd2ab3-95f8-5a7c-a91a-433f1bdf47b5
- DOI
- 10.1101/2021.06.23.449672