Article

Limited Expression of <i>Nrf2</i> in Neurons Across the Central Nervous System

2023-05-09

Abstract excerpt

Nrf2 is a broadly expressed transcription factor that regulates gene expression in response to reactive oxygen species (ROS) and oxidative stress. It is commonly referred to as a ubiquitous pathway, but this generalization overlooks work indicating that Nrf2 is essentially unexpressed in some neuronal populations. To explore whether this pattern extends throughout the central nervous system (CNS), we quantified N...

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Literature Corpus work: ce774e6c-c6df-53a5-b39e-61889ec44432
DOI: 10.1101/2023.05.09.540014

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