Article

Molecular Architecture of the Bardet-Biedl Syndrome Protein 2-7-9 Subcomplex

2019-07-11

Abstract excerpt

<h4>Summary</h4> Bardet-Biedl syndrome (BBS) is a genetic disease caused by mutations that disrupt the function of the BBSome, an eight-subunit complex that plays an important role in transport of proteins in primary cilia. To better understand the molecular basis of the disease, we analyzed the structure of a BBSome subcomplex consisting of three homologous BBS proteins (BBS2, BBS7, and BBS9) by an integrative s...

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Literature Corpus work: ce662647-33f1-5250-98d4-d1122601f84a
DOI: 10.1101/699223

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