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Article

Genomic Diversity of Azole-Resistant Aspergillus fumigatus in the United States.

mBio - 31 Aug 2021

Etienne Kizee A, Berkow Elizabeth L, Gade Lalitha, Nunnally Natalie, Lockhart Shawn R, Beer Karlyn, Jordan I King, Rishishwar Lavanya, Litvintseva Anastasia P

Abstract excerpt

Azole resistance in pathogenic Aspergillus fumigatus has become a global public health issue threatening the use of medical azoles. The environmentally occurring resistance mutations, TR34/L98H (TR34) and TR46/Y121F/T289A (TR46), are widespread across multiple continents and emerging in the United States. We used whole-genome single nucleotide polymorphism (SNP) analysis on 179 nationally represented clinical and...

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Source

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Identifiers

PMID: 34372699
DOI: 10.1128/mBio.01803-21
PMCID: PMC8406307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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