Article

Tumour Content Ratio Matters for Detecting Epidermal Growth Factor Receptor Mutation by Cobas Test in Small Biopsies; a Retrospective Study

2020-01-29

Abstract excerpt

<h4>Background: </h4> Recent studies indicate the benefit of treatment with osimertinib over that with conventional epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) for untreated EGFR -mutated non-small cell lung cancer (NSCLC). Cobas ver2 is the only companion diagnostic method for detecting EGFR mutations with osimertinib treatment. We clinically experience false negative cases with this...

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Literature Corpus work: ce5ae292-2951-5734-b46f-9b6becad0a2f
DOI: 10.21203/rs.2.16674/v3

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