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Article

Plasma ctDNA Analysis for Detection of the EGFR T790M Mutation in Patients with Advanced Non-Small Cell Lung Cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2017

Jenkins Suzanne, Yang James C-H, Ramalingam Suresh S, Yu Karen, Patel Sabina, Weston Susie, Hodge Rachel, Cantarini Mireille, Jänne Pasi A, Mitsudomi Tetsuya, Goss Glenwood D

Abstract excerpt

INTRODUCTION: Tumor biopsies for detecting EGFR mutations in advanced NSCLC are invasive, costly, and not always feasible for patients with late-stage disease. The clinical utility of the cobas EGFR Mutation Test v2 (Roche Molecular Systems, Inc., Pleasanton, CA) with plasma samples from patients with NSCLC at disease progression after previous EGFR tyrosine kinase inhibitor therapy was investigated to determine...

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PMID: 28428148
DOI: 10.1016/j.jtho.2017.04.003

Genes

EGFR

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