Article

ppIRIS: deep learning for proteome-wide prediction of bacterial protein-protein interactions

2025-09-24

Abstract excerpt

Protein-protein interactions (PPIs) are central to cellular processes and host-pathogen dynamics, yet bacterial interactomes remain poorly mapped, especially for extracellular effectors and cross-species interactions. Experimental approaches provide only partial coverage, while existing computational methods often lack generalizability or are too resource-intensive for proteome-scale application. Here, we introduc...

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Literature Corpus work: ce2e25cc-9093-560c-ac86-13ccc7ac3d75
DOI: 10.1101/2025.09.22.677885

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