Article

PEPPI: Whole-proteome protein-protein interaction prediction through structure and sequence similarity, functional association, and machine learning

2021-12-03

Abstract excerpt

Proteome-wide identification of protein-protein interactions is a formidable task which has yet to be sufficiently addressed by experimental methodologies. Many computational methods have been developed to predict proteome-wide interaction networks, but few leverage both the sensitivity of structural information and the wide availability of sequence data. We present PEPPI, a pipeline which integrates structural si...

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Literature Corpus work: a16272bc-28e2-5108-b19f-c24c92169394
DOI: 10.1101/2021.12.02.470917

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