Article

Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutations

2020-10-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Vaccination and anti-viral therapy with nucleos(t)ide analogues (NAs) are key approaches to reducing the morbidity, mortality and transmission of hepatitis B virus (HBV) infection. However, the efficacy of these interventions may be reduced by the emergence of drug resistance-associated mutations (RAMs) and/or vaccine escape mutations (VEMs). We have assimilated data on th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 23e976e6-ac1a-5879-b6b8-362c84a8d876
DOI: 10.1101/2020.10.07.329391

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutationsDOI 10.1101/2020.10.07.329391Read

Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutations.Semantic proximity Read

A systematic review of Hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: a call for urgent actionSemantic proximity Read

Immune Escape and Drug Resistance Mutations in Patients with Hepatitis B Virus Infection: Clinical and Epidemiological ImplicationsSemantic proximity Read

[Analysis on the sequence mutation and evolution of HBV genome in China].Semantic proximity Read

Comprehensive Analysis of Clinically Significant Hepatitis B Virus Mutations in Relation to Genotype, Subgenotype and Geographic RegionSemantic proximity Read

Evidence of Tenofovir Resistance in Chronic Hepatitis B Virus (HBV) Infection: An Observational Case Series of South African AdultsSemantic proximity Read

HBV evolution and genetic variability: Impact on prevention, treatment and development of antivirals.Semantic proximity Read

The evolution and clinical impact of hepatitis B virus genome diversity.Semantic proximity Read

Hepatitis B Virus Genotype D: An Overview of Molecular Epidemiology, Evolutionary History, and Clinical CharacteristicsSemantic proximity Read

Evolution and diversity of the hepatitis B virus genome: Clinical implications.Semantic proximity Read

Hepatitis B virus resistance substitutions: long-term analysis by next-generation sequencing.Semantic proximity Read

Hepatitis B virus resistance to tenofovir: fact or fiction? A systematic literature review and structural analysis of drug resistance mechanismsSemantic proximity Read