Article

First Report of Tenofovir Alafenamide Treatment Failure in Chronic Hepatitis B with Detection of Putative Tenofovir Resistance Mutations

2026-02-18

Abstract excerpt

Tenofovir alafenamide (TAF) is widely used for the treatment of chronic hepatitis B virus (HBV) infection and has been considered resistant to clinically significant antiviral resistance. We describe a 32-year-old woman with genotype C8 chronic HBV infection who had persistently elevated HBV DNA viral load despite documented adherence to entecavir and subsequent TAF therapy. After an initial virologic response to...

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Literature Corpus work: b12c56da-a58a-50a3-b96d-c825749fe244
DOI: 10.22541/au.177139637.76647554/v1

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