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Article

Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutations.

Journal of viral hepatitis - 1 Aug 2021

Mokaya Jolynne, Vasylyeva Tetyana I, Barnes Eleanor, Ansari M Azim, Pybus Oliver G, Matthews Philippa C

Abstract excerpt

Vaccination and anti-viral therapy with nucleos(t)ide analogues (NAs) are key approaches to reducing the morbidity, mortality and transmission of hepatitis B virus (HBV) infection. However, the efficacy of these interventions may be reduced by the emergence of drug resistance-associated mutations (RAMs) and/or vaccine escape mutations (VEMs). We have assimilated data on the global prevalence and distribution of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33893696
DOI: 10.1111/jvh.13525
PMCID: PMC8581767

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