Article

Dissecting intratumor heterogeneity of nodal B cell lymphomas on the transcriptional, genetic, and drug response level

2019-12-11

Abstract excerpt

Tumor heterogeneity encompasses both the malignant cells and their microenvironment. While heterogeneity between individual patients is well-known to affect the efficacy of anti-cancer drugs, most personalized treatment approaches do not account for intratumor heterogeneity. We addressed this issue by studying the heterogeneity of lymph node-derived B cell non-Hodgkin lymphoma (B-NHL) by single cell RNA-sequencing...

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Identifiers and source

Literature Corpus work: cdf31ce7-5144-5463-90c1-d51c8a698f61
DOI: 10.1101/850438

Open publication

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